Attacking malignant cells that survive therapy
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چکیده
منابع مشابه
Attacking malignant cells that survive therapy
We have recently defined "immunogenic modulation," a mechanism whereby malignant cells that survive anticancer therapy, due to sublethal delivery or development of treatment resistance, become nonetheless more sensitive to killing by cytotoxic T lymphocytes. This mechanism can be exploited to identify which therapies will best synergize with immunotherapy, potentially maximizing patient clinica...
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therapy acquire HIF-1 activity and translocate toward tumour blood vessels Hiroshi Harada, Masahiro Inoue, Satoshi Itasaka, Kiichi Hirota, Akiyo Morinibu, Kazumi Shinomiya, Lihua Zeng, Guangfei Ou, Yuxi Zhu, Michio Yoshimura, W Gillies Mckenna, Ruth J. Muschel & Masahiro Hiraoka Nature Communications 3:783; doi: 10.1038/ncomms1786 (2012); Published 17 Apr 2012; Updated 16 Oct 2013 In Fig. 2c,d ...
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Myocytes that survive in the epicardial border zone of the healing canine infarcted heart provide the substrate for inducible reentrant ventricular arrhythmias. These myocytes have been shown to have altered Ca currents which could impact on Ca homeostasis in these i cells. Objective and Methods: To directly measure and compare intracellular Ca transients and cell shortening in myocytes dispers...
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ژورنال
عنوان ژورنال: OncoImmunology
سال: 2013
ISSN: 2162-402X
DOI: 10.4161/onci.26937